ASSOCIATION OF PREECLAMPSIA WITH OLIGOHYDRAMNIOS DURING THE LAST TRIMESTER OF PREGNANCY

Authors

  • Afifa Niaz Department of Allied Health Sciences, Superior university Lahore, Pakistan Author
  • Rida Fatima M.Phil. molecular biology, M.Phil. hematology, Ph.D. scholar hematology, Department of Allied Health Sciences, Superior University Lahore, Pakistan Author

DOI:

https://doi.org/10.62019/vekf2837

Keywords:

Oligohydramnios, Pre-eclampsia, Amniotic Fluid Index (AFI, Uterine Doppler indices, Intrauterine Growth Restriction (IUGR)

Abstract

 

Introduction:

Preeclampsia is a complication of pregnancy. The patient suffers from high blood pressure and high levels of protein in urine that indicate kidney damage (proteinuria), or other signs of organ damage. Its poses significant maternal and fetal risks. It can lead to serious complications, including eclampsia, HELLP syndrome, along with maternal and fetal morbidity and mortality.

Aim of Study:

To determine the association of preeclampsia with oligohydramnios during last trimester.

Methods:

We conducted a cross-sectional study of 150 pregnant women with a mean age of 29.3 ± 5.9 years and a mean gestational age of 34.07 ± 2.4 weeks. Participants underwent clinical assessment, uterine artery Doppler ultrasonography, and measurement of amniotic fluid index (AFI). Chi-square tests were used to analyze associations between variables.

Results:

The prevalence of hypertension was 18%, diabetes 11.3%, and IUGR 14.7%. Mean AFI was 10.3 ± 3.7 cm. Uterine artery Doppler indices showed similar mean values for right and left arteries. Significant associations were found between hypertension and IUGR (p < 0.0001), hypertension and right uterine artery Doppler indices (p = 0.01), and hypertension and left uterine artery Doppler indices (p = 0.02). IUGR was significantly associated with both right (p = 0.031) and left (p = 0.008) uterine artery Doppler indices. No significant association was observed between hypertension and AFI (p = 0.766).

Conclusion:

 Our findings demonstrate strong relationships between hypertension, IUGR, and altered uterine artery blood flow in pregnancy. The lack of association between hypertension and AFI contrasts with some previous studies and warrants further investigation. These results underscore the importance of comprehensive monitoring in high-risk pregnancies, particularly focusing on fetal growth and uteroplacental blood-flow assessment.

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Published

2025-01-22

How to Cite

ASSOCIATION OF PREECLAMPSIA WITH OLIGOHYDRAMNIOS DURING THE LAST TRIMESTER OF PREGNANCY. (2025). Journal of Medical & Health Sciences Review, 2(1). https://doi.org/10.62019/vekf2837

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